Binifibrato, Binifibrate, WAC-104, Antopal retard, Biniwas-药物合成数据库

【药物名称】Binifibrato, Binifibrate, WAC-104, Antopal retard, Biniwas

化学结构式(Chemical Structure):

参考文献No.	49565
标题:	WAC-104
作者:	Casta馿r, J.
来源:	Drugs Fut 1979,4(9),681

合成路线图解说明: Sterification of 1,3-dichloro-2-propanol (I) with p-chlorophenoxyisobutyric acid (II) forms 1,3-dichloro-2-propanol 2-p-chlorophenoxyisobutirate (III), which, by reaction with the sodium salt of nicotinic acid, is transformed into trihydroxipropane 2-p-chlorophenoxyisobutyrate-1,3-dinicotinate.

参考文献No.	900142
标题:	Procedimiento para la obtenci髇 de un 閠er mixto sim閠rico del 1,2,3-trihidroxipropano
作者:	Andreoli, R.; Cirera, X. (Sociedad Espa駉la de Especialidades Farmaco-Terap閡ticas SA)
来源:	ES 463218

合成路线图解说明: Sterification of 1,3-dichloro-2-propanol (I) with p-chlorophenoxyisobutyric acid (II) forms 1,3-dichloro-2-propanol 2-p-chlorophenoxyisobutirate (III), which, by reaction with the sodium salt of nicotinic acid, is transformed into trihydroxipropane 2-p-chlorophenoxyisobutyrate-1,3-dinicotinate.