Xorphanol, TR-5379-药物合成数据库

【药物名称】Xorphanol, TR-5379

化学结构式(Chemical Structure):

参考文献No.	46744
标题:	17-Cyclobutylmethyl-3-hydroxy-beta-methyl-6-methylene morphinane, and methods of treating pain with them
作者:	Kotick, M.P.; Polazzi, J.O. (Bayer Corp.)
来源:	CA 1128508; EP 0027925; ES 8107222; US 4259329

合成路线图解说明: By a Wittig condensation of 17-cyclobutylmethyl-3-hydroxy-8beta-methyl morphinan-6-one (I) with triphenylmethylenephosphorane in DMSO.

参考文献No.	62065
标题:	TR-5379
作者:	Serradell, M.N.; Blancafort, P.; Casta馿r, J.
来源:	Drugs Fut 1982,7(1),40

合成路线图解说明: By a Wittig condensation of 17-cyclobutylmethyl-3-hydroxy-8beta-methyl morphinan-6-one (I) with triphenylmethylenephosphorane in DMSO.