【药物名称】Picotamide, G-137, Plactidil
化学结构式(Chemical Structure):
参考文献No.46985
标题:Inhibitor of blood plate aggregation
作者:Orzalesi, G.; Selleri, T. (L. Manetti & Roberts SpA)
来源:US 3973026
合成路线图解说明:

By condensation of 4-methoxyisophthaloyl chloride (I) with 3-picolylamine (II) by means of triethylamine in refluxing THF.

参考文献No.69360
标题:Picotamide
作者:Blancafort, P.; Serradell, M.N.; Casta馿r, J.; Hopkins, S.J.
来源:Drugs Fut 1980,5(1),37
合成路线图解说明:

By condensation of 4-methoxyisophthaloyl chloride (I) with 3-picolylamine (II) by means of triethylamine in refluxing THF.

参考文献No.700893
标题:Picolylamides de l'acide 4-hydroxy-isophalique, leurs d閞iv閟 m閠hoxyl?et 閠hoxyl?et leur proc閐?de fabrication
作者:Orzalesi, G.; Selleri, T.
来源:BE 0851967; FR 2100850
合成路线图解说明:

By condensation of 4-methoxyisophthaloyl chloride (I) with 3-picolylamine (II) by means of triethylamine in refluxing THF.

参考文献No.800223
标题:New 4-hydroxyisophatlic acid derivatives having anticoagulant and fibrinolytic activity
作者:Selleri, R.; et al.
来源:Chimie Th閞apeutique 1971,6(3),203-207
合成路线图解说明:

By condensation of 4-methoxyisophthaloyl chloride (I) with 3-picolylamine (II) by means of triethylamine in refluxing THF.

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