【药物名称】PFS-1144, EO-122
化学结构式(Chemical Structure):
参考文献No.63031
标题:EO-122
作者:Oppenheimer, E.; Binah, O.
来源:Drugs Fut 1988,13(8),724
合成路线图解说明:

The synthesis of EO 122 starts from quinuclidine-3-carboxylic acid (I), which is converted to the acid chloride (II) by oxalyl chloride. The addition of 2,6-dimethylaniline (III) to the acid chloride yields EO-122.

参考文献No.546582
标题:A preclinical study of EO-122, a new lidocaine-lik
作者:Oppenheimer, E.; Kaplinsky, E.; Kariv, E.; Bruckstein, R.; Cohen, S.
来源:Angiology 1980,31410
合成路线图解说明:

The synthesis of EO 122 starts from quinuclidine-3-carboxylic acid (I), which is converted to the acid chloride (II) by oxalyl chloride. The addition of 2,6-dimethylaniline (III) to the acid chloride yields EO-122.

参考文献No.546587
标题:Studie in the quinudidine line. 3-Quinudialine-car
作者:Renk, E.; Grob, C.A.
来源:Helv Chim Acta 1954,371689
合成路线图解说明:

The synthesis of EO 122 starts from quinuclidine-3-carboxylic acid (I), which is converted to the acid chloride (II) by oxalyl chloride. The addition of 2,6-dimethylaniline (III) to the acid chloride yields EO-122.

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