BR-227-药物合成数据库

【药物名称】BR-227

化学结构式(Chemical Structure):

参考文献No.	46002
标题:	2-Benzoylamino substituted benzylamine derivative and a process for preparation thereof
作者:	Koshinaka, E.; Ogawa, N.; Kurata, S.; Yamagashi, K.; Kato, I. (Hokuriku Seiyaku Co., Ltd.)
来源:	DE 3209970; EP 0061157; ES 510608

合成路线图解说明: The acylation of 2,4-dibromo-6-(N-cyclohexyl-N-methylaminomethyl)aniline (I) with 4-(ethoxycarbonyloxy)-3-methoxybenzoyl chloride (II) in CHCl3 gives the corresponding amide (III), which is deprotected by a treatment with aqueous 20% NaOH.

参考文献No.	74465
标题:	BR-227
作者:	Chu, S.S.
来源:	Drugs Fut 1985,10(3),186

合成路线图解说明: The acylation of 2,4-dibromo-6-(N-cyclohexyl-N-methylaminomethyl)aniline (I) with 4-(ethoxycarbonyloxy)-3-methoxybenzoyl chloride (II) in CHCl3 gives the corresponding amide (III), which is deprotected by a treatment with aqueous 20% NaOH.