【药物名称】INO-2628(free base), INO-2628CZ
化学结构式(Chemical Structure):
参考文献No.46036
标题:Cyclopropylmethyl piperazines, the process for preparing the same and their use in therapeutics
作者:Robba, M.F.; Aurousseau, M.E. (Laboratoire Innothera SA)
来源:CA 1171085; EP 81401516; FR 8021527; JP 163681; US 4474783
合成路线图解说明:

The reaction of cyclopropylmethyl chloride or cyclopropylmethyl bromide (Ia-b) with piperazine (II) by means of Na2CO3 in anhydrous DMF gives N,N-dicyclopropylmethylpiperazine.

参考文献No.77508
标题:INO-2628 CZ
作者:Leclerc, G.
来源:Drugs Fut 1985,10(11),907
合成路线图解说明:

The reaction of cyclopropylmethyl chloride or cyclopropylmethyl bromide (Ia-b) with piperazine (II) by means of Na2CO3 in anhydrous DMF gives N,N-dicyclopropylmethylpiperazine.

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