Cinitapride hygrogen tartrate, LAS-17177, Blaston, Cidine-药物合成数据库

【药物名称】Cinitapride hygrogen tartrate, LAS-17177, Blaston, Cidine

化学结构式(Chemical Structure):

参考文献No.	16725
标题:	Piperidine cpds
作者:	Boix Iglesias, J.; Prieto Soto, J.; Vega Nogerola, A.; Moragues Mauri, J.
来源:	GB 1574419

合成路线图解说明: This compound can be obtained by a process which comprises reacting 4-amino-2-ethoxy-5-nitrobenzoic acid (I) with 4-amino-1-(3-cyclohexen-1-ylmethyl)piperidine (II) in the presence of triethylamine and ethyl chloroformate. The resulting free base (III) is salified with L-(+)-tartaric acid to give the corresponding salt.

参考文献No.	151174
标题:	Cinitapride Hydrogen Tartrate
作者:	Roberts, D.J.; Fernandez, A.G.
来源:	Drugs Fut 1991,16(10),885

合成路线图解说明: This compound can be obtained by a process which comprises reacting 4-amino-2-ethoxy-5-nitrobenzoic acid (I) with 4-amino-1-(3-cyclohexen-1-ylmethyl)piperidine (II) in the presence of triethylamine and ethyl chloroformate. The resulting free base (III) is salified with L-(+)-tartaric acid to give the corresponding salt.