Iomorinate sodium, ST-5614, Oravesin-药物合成数据库

【药物名称】Iomorinate sodium, ST-5614, Oravesin

化学结构式(Chemical Structure):

参考文献No.	701269
标题:
作者:	Obendorf, W.; Schwarzinger, E.; Krieger, J.; Lindner, I.
来源:	DE 2235935; DE 3000215

合成路线图解说明: The title compound was prepared by reacting 3-amino-2,4,6-triiodobenzoyl chloride (I) with alpha-methyl-beta-aminopropionitrile (II) in DMF and subsequently by treatment of the intermediary amine (III) with N-acetylmorpholine (IV) to yield the nitrile (V), which was then hydrolyzed with HCl.

参考文献No.	800369
标题:	Iomorinic acid
作者:	Koch, H.
来源:	Drugs Fut 1983,8(10),855

合成路线图解说明: The title compound was prepared by reacting 3-amino-2,4,6-triiodobenzoyl chloride (I) with alpha-methyl-beta-aminopropionitrile (II) in DMF and subsequently by treatment of the intermediary amine (III) with N-acetylmorpholine (IV) to yield the nitrile (V), which was then hydrolyzed with HCl.