【药物名称】Butoctamide hemisuccinate, Listomin
化学结构式(Chemical Structure):
参考文献No.41870
标题:N-Substd.-beta-oxybutyramide semisuccinate and its salt having effects of increasing paradoxical sleep and tranquillizing
作者:Yamagisawa, I.; Torii, S.; Sakuma, A. (Lion Corp.)
来源:DE 1768445; US 3639457
合成路线图解说明:

The reaction of diketene (I) with 2-ethylhexylamine (II) gives N-(2-ethylhexyl)acetoacetamide (III), which is reduced to the target compound with H2 over Raney-Ni in methanol.

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