Budesonide, S-1320, Pulmaxan, Pulmicort, Rhinocort, Entocort, Budenofalk, Preferid, Pulmicort turbuhaler, Budiair, Pulmaxan turbohaler, Pulmicort Topinasal, Pulmicort Respules, Inflammide, Giona Easyhaler, Miflonide, Rhinocort Aqua-药物合成数据库

【药物名称】Budesonide, S-1320, Pulmaxan, Pulmicort, Rhinocort, Entocort, Budenofalk, Preferid, Pulmicort turbuhaler, Budiair, Pulmaxan turbohaler, Pulmicort Topinasal, Pulmicort Respules, Inflammide, Giona Easyhaler, Miflonide, Rhinocort Aqua

化学结构式(Chemical Structure):

参考文献No.	201760
标题:	Budesonide
作者:	Dharma, A.P.
来源:	Drugs Fut 1980,5(4),179

合成路线图解说明: From 16alpha-hydroxyprednisolone (III) and n-butyraldehyde (A) in the presence of an acid catalyst. Budesonide is defined as a 1:1 mixture of the two epimers (I) and (II).

参考文献No.	604513
标题:	Synthesis and antiinflammatory properties of budesonide, a new nonhalogenated glucocorticoid with high local activity
作者:	Thal閚, A.; Brattsand, R.
来源:	Arzneim-Forsch Drug Res 1979,29(11),1687-90

合成路线图解说明: From 16alpha-hydroxyprednisolone (III) and n-butyraldehyde (A) in the presence of an acid catalyst. Budesonide is defined as a 1:1 mixture of the two epimers (I) and (II).