Toloxatone, MD-69276, Umoril, Humoryl, Perenum-药物合成数据库

【药物名称】Toloxatone, MD-69276, Umoril, Humoryl, Perenum

化学结构式(Chemical Structure):

参考文献No.	201759
标题:	Toloxatone
作者:	Sungurbey, K.; Casta馿r, J.
来源:	Drugs Fut 1976,1(12),569

合成路线图解说明: By condensation of m-toluidine (I) and glycidol (II) in methanol to give 3-(m-toluidino)-1,2-propanediol (III), which was then cyclized by condensation with ethyl carbonate (A) by means of NaOCH3.

参考文献No.	800289
标题:	Une nouvelle serie d'antid閜resseurs: les deriv閟 de l'hydroxym閠hyl-5-oxazolidinone-2
作者:	Douzon, C.; Fauvan, C.
来源:	Chimie Th閞apeutique 1973,3324-327

合成路线图解说明: By condensation of m-toluidine (I) and glycidol (II) in methanol to give 3-(m-toluidino)-1,2-propanediol (III), which was then cyclized by condensation with ethyl carbonate (A) by means of NaOCH3.