Norfloxacin, MK-0366, AM-715, Norflo, Lexinor, Baccidal, Sebercim, Noroxin, Fulgram, Barazan-药物合成数据库

【药物名称】Norfloxacin, MK-0366, AM-715, Norflo, Lexinor, Baccidal, Sebercim, Noroxin, Fulgram, Barazan

化学结构式(Chemical Structure):

参考文献No.	47502
标题:	Piperazinyl derivs. of quinoline carboxylic acids
作者:	Irikura, T. (Kyorin Pharmaceutical Co., Ltd.)
来源:	US 4146719

合成路线图解说明: By condensation of 1-ethyl-6-fluoro-7-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid (I) with piperazine (II) by heating at 170 C in water in a pressure tube.

参考文献No.	800455
标题:	AM-715
作者:	Blancafort, P.; Sweetman, A.J.; Casta馿r, J.; Serradell, M.N.
来源:	Drugs Fut 1981,6(8),462

合成路线图解说明: By condensation of 1-ethyl-6-fluoro-7-chloro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid (I) with piperazine (II) by heating at 170 C in water in a pressure tube.