Elliptinium acetate, NSC-264137, HME, Celiptium-药物合成数据库

【药物名称】Elliptinium acetate, NSC-264137, HME, Celiptium

化学结构式(Chemical Structure):

参考文献No.	47004
标题:	Derivatives of 9-hydroxy-ellipticine and a process fo their preparation
作者:	Le Pecq, J.B.; et al. (ANVAR (Agence Natl. Valor. Rech.))
来源:	CH 616937; DE 2618223; FR 2308365; GB 1508388

合成路线图解说明: The iodide is formed as follows: 9-Methoxy-ellipticine (I) (extracted from Ochrosia maculata) is demethylated by refluxing with pyridine hydrochloride to give 9-hydroxy-ellipticine (II), which is then treated with methyl iodide in DMF at room temperature.

参考文献No.	201780
标题:	NSC-264137
作者:	Woodman, R.J.
来源:	Drugs Fut 1979,4(4),267

合成路线图解说明: The iodide is formed as follows: 9-Methoxy-ellipticine (I) (extracted from Ochrosia maculata) is demethylated by refluxing with pyridine hydrochloride to give 9-hydroxy-ellipticine (II), which is then treated with methyl iodide in DMF at room temperature.