Tiapride hydrochloride, Gramalil, Tiapridal-药物合成数据库

【药物名称】Tiapride hydrochloride, Gramalil, Tiapridal

化学结构式(Chemical Structure):

参考文献No.	313534
标题:	Tiapride
作者:	Neuman, M.; Prous, J.R.
来源:	Drugs Fut 1976,1(2),88

合成路线图解说明: Prepared by reacting 2-methoxy-5-methylsulfonylbenzoic acid (I) with isobutyl chloroformate (A) in dioxane to give the corresponding anhydride (II), which is finally condensed with N,N-diethylethylenediamine (B).

参考文献No.	701115
标题:	Process for preparing benzamides
作者:	Bulteau, G.; Acher, J.
来源:	CH 585699; DE 2327192; GB 1394563; JP 49085037

合成路线图解说明: Prepared by reacting 2-methoxy-5-methylsulfonylbenzoic acid (I) with isobutyl chloroformate (A) in dioxane to give the corresponding anhydride (II), which is finally condensed with N,N-diethylethylenediamine (B).