*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : AB2625000 CHEMICAL NAME : Acetaldehyde, chloro-, (2,4-dinitrophenyl)hydrazone CAS REGISTRY NUMBER : 5135-80-8 BEILSTEIN REFERENCE NO. : 0673855 REFERENCE : 3-15-00-00427 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 8 MOLECULAR FORMULA : C8-H7-Cl-N4-O4 MOLECULAR WEIGHT : 258.64 WISWESSER LINE NOTATION : WNR CNW DMNU2G COMPOUND DESCRIPTOR : Agricultural Chemical SYNONYMS/TRADE NAMES : * Chloracetaldehyd-2,4-dinitrofenylhydrazon * Chloroacetaldehyde (2,4-dinitrophenyl)hydrazone * Monochloroacetaldehyde 2,4-dinitrophenylhydrazone * Olin 1763 * OM1763 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >40 mL/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,472,1966 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : >40 mL/kg TOXIC EFFECTS : Gastrointestinal - nausea or vomiting REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,472,1966 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 1460 mg/kg TOXIC EFFECTS : Gastrointestinal - nausea or vomiting REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,472,1966 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 6825 mg/kg/13W-C TOXIC EFFECTS : Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Endocrine - changes in spleen weight REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,472,1966 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 70 gm/kg/1Y-C TOXIC EFFECTS : Endocrine - changes in spleen weight Related to Chronic Data - changes in testicular weight REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,472,1966 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 65 gm/kg/97W-C TOXIC EFFECTS : Endocrine - changes in spleen weight Related to Chronic Data - changes in testicular weight REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,472,1966 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 3412 mg/kg/13W-C TOXIC EFFECTS : Behavioral - rigidity (including catalepsy) Peripheral Nerve and Sensation - fasciculations REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,472,1966 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Bird - chicken DOSE/DURATION : 105 gm/kg/60D-C TOXIC EFFECTS : Behavioral - muscle weakness Related to Chronic Data - death REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 8,472,1966 *** END OF RECORD ***