*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AB4318000
CHEMICAL NAME           : Acetamide, 2-(4-allyl-2-methoxyphenoxy)-N,N-diethyl-
CAS REGISTRY NUMBER     : 305-13-5
BEILSTEIN REFERENCE NO. : 2472368
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C16-H23-N-O3
MOLECULAR WEIGHT        : 277.40
WISWESSER LINE NOTATION : 2N2&V1OR BO1 D2U1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-(4-Allyl-2-methoxyphenoxy)-N,N-diethylacetamide
   * Detrovel
   * Diethylamide de l'acide eugenol-glycolique
   * Diethylamide du 2-methoxy-4-allylphenoxyacetique
   * N,N-Dietilamide dell'acido 2-metossi-4-allil-fenossiacetico
   * Estil
   * Eunal
   * G 29505
   * 2-Methoxy-4-allylphenoxyaceticic acid-N,N-diethylamide
   * 2-Methoxy-4-allylphenoxyessigsaeure-N,N-diaethylamid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 38 mg/kg
TOXIC EFFECTS :
   Behavioral - coma
   Cardiac - cardiac output
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AAREAV Anesthesie, Analgesie, Reanimation.  (Paris, France)  V.14-38,
   1957-81.  Volume(issue)/page/year: 15,853,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 840 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   JMPCAS Journal of Medicinal and Pharmaceutical Chemistry.  (Washington, DC)
   V.1-5, 1959-62.  For publisher information, see JMCMAR.
   Volume(issue)/page/year: 4,317,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 475 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   JMPCAS Journal of Medicinal and Pharmaceutical Chemistry.  (Washington, DC)
   V.1-5, 1959-62.  For publisher information, see JMCMAR.
   Volume(issue)/page/year: 4,317,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 29 mg/kg
TOXIC EFFECTS :
   Behavioral - coma
   Cardiac - cardiac output
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AAREAV Anesthesie, Analgesie, Reanimation.  (Paris, France)  V.14-38,
   1957-81.  Volume(issue)/page/year: 15,853,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 55 mg/kg
TOXIC EFFECTS :
   Behavioral - coma
   Cardiac - cardiac output
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   AAREAV Anesthesie, Analgesie, Reanimation.  (Paris, France)  V.14-38,
   1957-81.  Volume(issue)/page/year: 15,853,1958
 
                            *** END OF RECORD ***