*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : AB5750000
CHEMICAL NAME : Acetamide,
N-(2-(6-chloro-5-methoxy-1H-indol-3-yl)ethyl)-
CAS REGISTRY NUMBER : 63762-74-3
BEILSTEIN REFERENCE NO. : 0410191
REFERENCE : 5-22-12-00064 (Beilstein Handbook Reference)
LAST UPDATED : 199612
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C13-H15-Cl-N2-O2
MOLECULAR WEIGHT : 266.75
WISWESSER LINE NOTATION : T56 BMJ D2MV1 GO1 HG
COMPOUND DESCRIPTOR : Reproductive Effector
SYNONYMS/TRADE NAMES :
* 6-Chloromelatonin
* N-(2-(6-Chloro-5-methoxy-1H-indol-3-yl)ethyl)acetamide
*** HEALTH HAZARD DATA ***
** REPRODUCTIVE DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 4 mg/kg
SEX/DURATION : female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 22,63,1979
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intravenous
SPECIES OBSERVED : Rodent - rat
DOSE : 4 mg/kg
SEX/DURATION : female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - other measures of fertility
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc.,
Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
20037) V.6- 1963- Volume(issue)/page/year: 22,63,1979
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - hamster
DOSE : 1260 ug/kg
SEX/DURATION : female 9 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - ovaries, fallopian tubes
Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot,
POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960-
Volume(issue)/page/year: 78,381,1986
*** END OF RECORD ***