*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AB5839000
CHEMICAL NAME           : Acetamide,
                          2-chloro-N-(5,6,7,9-tetrahydro-1,2,3-trimethoxy-10-(m
                          ethylthio)-9-oxobenzo (a) heptalen-7-yl)-, (S)-
CAS REGISTRY NUMBER     : 38479-08-2
BEILSTEIN REFERENCE NO. : 2790213
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H24-Cl-N-O5-S
MOLECULAR WEIGHT        : 449.98
WISWESSER LINE NOTATION : L B677 MV&T&J CO1 DO1 EO1 JMV1G NS1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 17-Chloro-10-demethoxy-10-methylthiocolchicine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1007 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 24,636,1981
 
                            *** END OF RECORD ***