*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AB7453000
CHEMICAL NAME           : Acetamide,
                          N-(3,4-dihydro-4-oxo-3-quinazolinylmethyl)-2-(N-ethyl
                          anilino)-, trihydrochloride
CAS REGISTRY NUMBER     : 70395-18-5
LAST UPDATED            : 198212
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H20-N4-O2.3Cl-H
MOLECULAR WEIGHT        : 445.81
WISWESSER LINE NOTATION : T66 BVN ENJ C1MV1N2&R &GH 3
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Acetamide, 2-(ethylphenylamino)-N-((4-oxo-3(4H)-quinazolinyl)methyl)-,  
   3HCl
   * N-(3,4-Dihydro-4-oxo-3-quinazolinylmethyl)-2-(N-ethylanilino)acetamide  
   trihydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   IJSIDW Indian Journal of Pharmaceutical Sciences.  (Kalina, Santa Cruz
   (East), Bombay 400 029, India)  V.40(2)-    1978-  Volume(issue)/page/year:
   41,33,1979
 
                            *** END OF RECORD ***