*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AB7455000
CHEMICAL NAME           : Acetamide,
                          2-((1,2-dihydro-5,6,17,19,21-pentahydroxy-23-methoxy-
                          2,4,12,16,18,20,22-
                          heptamethyl-1,11-dioxo-2,7-(epoxypentadeca(1,11,13)tr
                          ienimino)naphtho(2,1- b)furan-9-yl)oxy)-
                          N-benzyl-N-methyl-, 21-acetate
CAS REGISTRY NUMBER     : 17607-40-8
BEILSTEIN REFERENCE NO. : 5418810
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C47-H58-N2-O13
MOLECULAR WEIGHT        : 859.07
WISWESSER LINE NOTATION : T-24-5 B6 C6 A D E 2BC G& AV GMV WO B&O IU KU UU
                          A&HT&&&J DO1VN1&1 I1 M1 NQ O1 PQ Q1 ROV1 S1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * NCI 143-433
   * Rifamycin B benzylmethylamide
   * Rifamycin, 4-O-(2-(methyl(phenylmethyl)amino)-2-oxoethyl)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 222 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 7,596,1964
 
                            *** END OF RECORD ***