*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AB7911600
CHEMICAL NAME           : Acetamide,
                          N-(3-(dimethylamino)propyl)-2-((4-oxo-2-phenyl-4H-1-b
                          enzopyran-7-yl)oxy)-
CAS REGISTRY NUMBER     : 607-75-0
BEILSTEIN REFERENCE NO. : 1298536
REFERENCE               : 5-18-02-00264 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C22-H24-N2-O4
MOLECULAR WEIGHT        : 380.48
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (gamma-Dimethylaminopropyl)-amid der flavon-7-oxyessigsaeure
   *   N-(3-(Dimethylamino)propyl)-2-((4-oxo-2-phenyl-4H-1-benzopyran-7-yl)oxy)
     acetamide
   * FLA 22
   * Flavon-7-oxyessigsaeure-(gamma-dimethylaminopropyl)amid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1170 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   ABMGAJ Acta Biologica et Medica Germanica.  (Berlin, Ger. Dem. Rep.) V.1-41,
   1958-82.  For publisher information, see BBIADT. Volume(issue)/page/year:
   14,336,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Cardiac - pulse rate
REFERENCE :
   ABMGAJ Acta Biologica et Medica Germanica.  (Berlin, Ger. Dem. Rep.) V.1-41,
   1958-82.  For publisher information, see BBIADT. Volume(issue)/page/year:
   14,355,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 302 mg/kg
TOXIC EFFECTS :
   Cardiac - pulse rate
REFERENCE :
   ABMGAJ Acta Biologica et Medica Germanica.  (Berlin, Ger. Dem. Rep.) V.1-41,
   1958-82.  For publisher information, see BBIADT. Volume(issue)/page/year:
   14,355,1965
 
                            *** END OF RECORD ***