*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AB8050500
CHEMICAL NAME           : Acetamide,
                          N-(5-(((1,1-dimethylethyl)amino)sulfonyl)-1,3,4-thiad
                          iazol-2-yl)-, monosodium salt
LAST UPDATED            : 198910
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C8-H14-N4-O3-S2.Na
MOLECULAR WEIGHT        : 301.37
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * CL 13,850 sodium
   * N-(5-(((1,1-Dimethylethyl)amino)sulfonyl)-1,3,4-thiadiazol-2-yl)acetamide 
    monosodium salt
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 400 mg/kg
SEX/DURATION            : female 10-11 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
   e.g., stunted fetus)
REFERENCE :
   JHMJAX Johns Hopkins Medical Journal.  (Baltimore, MD)  V.120-151, 1967-82.
   Discontinued.  Volume(issue)/page/year: 130,95,1972
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 200 mg/kg
SEX/DURATION            : female 10-11 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Newborn - other neonatal measures or effects
REFERENCE :
   JHMJAX Johns Hopkins Medical Journal.  (Baltimore, MD)  V.120-151, 1967-82.
   Discontinued.  Volume(issue)/page/year: 130,95,1972
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 600 mg/kg
SEX/DURATION            : female 10-11 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   JHMJAX Johns Hopkins Medical Journal.  (Baltimore, MD)  V.120-151, 1967-82.
   Discontinued.  Volume(issue)/page/year: 130,95,1972
 
                            *** END OF RECORD ***