*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AB8570000
CHEMICAL NAME           : Acetamide,
                          N-(1-(2-(4-ethyl-4,5-dihydro-5-oxo-1H-tetrazol-1-yl)e
                          thyl)-3-methyl-4-pipe
                          ridinyl)-N-(2-fluorophenyl)-2-methoxy-,
                          monohydrochloride, cis-(+-)-
CAS REGISTRY NUMBER     : 117268-95-8
LAST UPDATED            : 199403
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H29-F-N6-O3.Cl-H
MOLECULAR WEIGHT        : 457.01
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * A 3331
   * Brifentanil hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 53 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   16,706,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 191 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year:
   16,706,1991
 
                            *** END OF RECORD ***