*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BR4025000
CHEMICAL NAME           : Ammonium, (m-hydroxyphenyl)trimethyl-, iodide,
                          dimethylcarbamate
CAS REGISTRY NUMBER     : 1212-37-9
LAST UPDATED            : 199109
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C12-H19-N2-O2.I
MOLECULAR WEIGHT        : 350.23
WISWESSER LINE NOTATION : 1N1&VOR CK1&1&1 &I
SYNONYMS/TRADE NAMES :
   * Ammonium, (3-(dimethylcarbamoyloxy)phenyl)trimethyl-, iodide
   * Benzenaminium, 3-(((dimethylamino)carbonyl)oxy)-N,N,N-trimethyl-, iodide
   * Carbamic acid, N,N-dimethyl-, 3-dimethylaminophenyl ester, methiodide
   * Carbamic acid, dimethyl-, m-(trimethylammonio)phenyl ester, iodide
   * Neostigmine iodide
   * SB-24
   * TL-1321
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 475 ug/kg
TOXIC EFFECTS :
   Behavioral - coma
   Lungs, Thorax, or Respiration - respiratory stimulation
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB158-508
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 165 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: -,800,1990
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 7449 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: -,800,1990
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 171 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: -,800,1990
 
                            *** END OF RECORD ***