*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BR7167000
CHEMICAL NAME           : Ammonium, (2-methoxyallyl)trimethyl-, bromide
CAS REGISTRY NUMBER     : 590-31-8
LAST UPDATED            : 199206
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C7-H16-N-O.Br
MOLECULAR WEIGHT        : 210.15
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Esmodil
   * Esmodyl
   * Meprochol
   * 2-Methoxy-N,N,N-trimethyl-2-propen-1-aminium bromide
   * 2-Propen-1-aminium, 2-methoxy-N,N,N-trimethyl-, bromide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - miosis (pupillary constriction)
   Cardiac - pulse rate
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
   Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
    Volume(issue)/page/year: -,397,1948
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 1 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - miosis (pupillary constriction)
   Cardiac - pulse rate
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
   Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
    Volume(issue)/page/year: -,397,1948
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - miosis (pupillary constriction)
   Cardiac - pulse rate
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
   Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
    Volume(issue)/page/year: -,397,1948
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 1 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - miosis (pupillary constriction)
   Cardiac - pulse rate
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme
   Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948
    Volume(issue)/page/year: -,397,1948
 
                            *** END OF RECORD ***