*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BR8140000
CHEMICAL NAME           : Ammonium,
                          (1-methyl-2-(phenothiazin-10-yl)ethyl)trimethyl-,
                          iodide
CAS REGISTRY NUMBER     : 26212-80-6
LAST UPDATED            : 199203
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C18-H23-N2-S.I
MOLECULAR WEIGHT        : 426.39
WISWESSER LINE NOTATION : T C666 BN ISJ B1Y1&K1&1&1 &Q &I
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Ammonium, (1-(phenothiazin-10-yl)-2-propyl)trimethyl-, iodide
   * Ammonium, trimethyl(1-methyl-2-phenothiazin-10-ylethyl)-, iodide
   * 10H-Phenothiazine-10-ethanaminium, N,N,N,alpha-tetramethyl-, iodide
   * (1-(Phenothiazin-10-yl)-2-propyl)trimethylammonium iodide
   * Promethazine methiodide
   * Thiazinamium
   * Thiazinamium iodide
   * Trimethylammonium-isopropyl-phenthiazin jodid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 120,450,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 11 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 120,450,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 6 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 120,450,1959
 
                            *** END OF RECORD ***