*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : BU2830000
CHEMICAL NAME           : Amphotericin B, 5,8,9-trideoxy-7,10-dihydroxy-5-oxo-,
                          monosodium salt
CAS REGISTRY NUMBER     : 75442-91-0
OTHER CAS REGISTRY NOS. : 104154-08-7
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C47-H71-N-O17.Na
MOLECULAR WEIGHT        : 945.18
WISWESSER LINE NOTATION : T-40-O DV JV PV WU B&U D&U F&U H&U J&U L&UTJ FQ HQ MQ
                          NQ RQ SVO TQ N&1 O&Q P&1 Q&1 VO- BT6OTJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Mycoheptin sodium salt
   * Sodium salt of mycoheptin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANTBAL Antibiotiki.  (Moscow, USSR)  V.1-29, 1956-84.  For publisher
   information, see AMBIEH.  Volume(issue)/page/year: 25,669,1980
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ANTBAL Antibiotiki.  (Moscow, USSR)  V.1-29, 1956-84.  For publisher
   information, see AMBIEH.  Volume(issue)/page/year: 25,669,1980
 
                            *** END OF RECORD ***