*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TN2855000
CHEMICAL NAME           : 1-Piperidinepropanol, alpha,alpha-diphenyl-
CAS REGISTRY NUMBER     : 511-45-5
BEILSTEIN REFERENCE NO. : 0252983
REFERENCE               : 5-20-02-00247 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H25-N-O
MOLECULAR WEIGHT        : 295.46
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 238 C
   * alpha,alpha-Diphenyl-1-piperidinepropanol
   * HH 212
   * Nonplesin
   * Parks
   * Parks 12
   * Parks 12 hommel
   * PDP
   * Pridinol
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   CHTPBA Chimica Therapeutica.  (Paris, France)  V.1-8, 1965-73.  For
   publisher information, see EJMCA5.  Volume(issue)/page/year: 1,212,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 193 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 23,8,1960
 
                            *** END OF RECORD ***