*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TN2856000
CHEMICAL NAME           : 1-Piperidinepropanol, alpha,alpha-diphenyl-,
                          hydrochloride
CAS REGISTRY NUMBER     : 968-58-1
LAST UPDATED            : 199606
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C20-H25-N-O.Cl-H
MOLECULAR WEIGHT        : 331.92
WISWESSER LINE NOTATION : T6NTJ A2XQR&R &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Benzhydrol, alpha-(2-piperidylethyl)-, hydrochloride
   * alpha,alpha-Diphenyl-1-piperidinepropanol hydrochloride
   * 1,1-Diphenyl-3-piperidino-1-propanol hydrochloride
   * 1,1-Diphenyl-3-(1-piperidyl)-1-propanol hydrochloride
   * Mitanoline
   * Par KS-12
   * 3-Piperidino-1,1-diphenyl-1-propanol hydrochloride
   * 3-(N-Piperidyl)-1,1-diphenyl-1-propanol hydrochloride
   * alpha-(2-Piperidylethyl) benzhydrol hydrochloride
   * Pridinol hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 91 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 96,151,1949
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 33 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 96,151,1949
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 131 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 96,151,1949
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 116,177,1956
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 1500 mg/kg/15W-I
TOXIC EFFECTS :
   Behavioral - irritability
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 96,151,1949
 
                            *** END OF RECORD ***