*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TN1941000
CHEMICAL NAME           : Piperidine, 1-methyl-3-(thioxanthen-9-ylmethyl)-
CAS REGISTRY NUMBER     : 4969-02-2
BEILSTEIN REFERENCE NO. : 0267181
REFERENCE               : 4-27-00-01421 (Beilstein Handbook Reference)
LAST UPDATED            : 199712
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H23-N-S
MOLECULAR WEIGHT        : 309.50
WISWESSER LINE NOTATION : T C666 BSJ I1- CT6NTJ A1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Methixen
   * 1-Methyl-3-(thioxanthen-9-ylmethyl) piperidine
   * Metixene
   * 60 SJ 1977
   * Tremaril
   * Tremonil
   * Trest
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 430 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 14,89,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 18 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 14,89,1964
 
                            *** END OF RECORD ***