*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TN2145000
CHEMICAL NAME           : Piperidine, 1-nitroso-2,2,6,6-tetramethyl-
CAS REGISTRY NUMBER     : 6130-93-4
BEILSTEIN REFERENCE NO. : 0119935
REFERENCE               : 5-20-04-00252 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C9-H18-N2-O
MOLECULAR WEIGHT        : 170.29
WISWESSER LINE NOTATION : T6NTJ ANO B1 B1 F1 F1
COMPOUND DESCRIPTOR     : Tumorigen
                          Drug
SYNONYMS/TRADE NAMES :
   * 1-Nitroso-2,2,6,6-tetramethylpiperidine
   * 2,2,6,6-Tetramethylnitrosopiperidine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NATUAS Nature.  (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
   V.1-    1869-  Volume(issue)/page/year: 184,1707,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 25 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NATUAS Nature.  (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736)
   V.1-    1869-  Volume(issue)/page/year: 184,1707,1959
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3375 mg/kg/50W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Sense Organs and Special Senses (Olfaction) - tumors
   Liver - tumors
REFERENCE :
   IJCNAW International Journal of Cancer.  (International Union Against
   Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland)  V.1-    1966-
   Volume(issue)/page/year: 16,318,1975
 
                            *** END OF RECORD ***