*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TN6157600 CHEMICAL NAME : Piperidinium, 1,1'-(1,4-piperazinediyldiethylene)bis(1-methyl-, diiodide CAS REGISTRY NUMBER : 99887-45-3 LAST UPDATED : 198909 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C20-H42-N4.2I MOLECULAR WEIGHT : 592.46 WISWESSER LINE NOTATION : T6N DNTJ A2- AT6KTJ A1& D2- AT6KTJ A1 &I 2 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * 334 HC * 1,1'-(1,4-Piperazinediyldiethylene)bis(1-methylpiperidinium iodide) *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 75 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - other changes REFERENCE : THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 9,314,1954 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 20 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 94,1,1953 *** END OF RECORD ***