*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TN7848000
CHEMICAL NAME           : 4-Piperidinol, N-nitroso-
CAS REGISTRY NUMBER     : 55556-93-9
BEILSTEIN REFERENCE NO. : 1447942
REFERENCE               : 5-21-01-00076 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C5-H10-N2-O2
MOLECULAR WEIGHT        : 130.17
WISWESSER LINE NOTATION : T6NTJ ANO DQ
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * N-Nitroso-4-hydroxypiperidine
   * Nitroso-4-piperidinol
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1666 mg/kg/36W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Sense Organs and Special Senses (Olfaction) - tumors
   Liver - tumors
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   55,705,1975
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 400 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 56,131,1977

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: Histidine reversion-Ames test
   
   EPA GENETOX PROGRAM 1988, Inconclusive: D melanogaster-whole sex chrom. loss
   
   EPA GENETOX PROGRAM 1988, Inconclusive: D melanogaster-partial sex chrom.
   loss
   
   EPA GENETOX PROGRAM 1988, Inconclusive: D melanogaster Sex-linked lethal

 
                            *** END OF RECORD ***