*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TO7874000
CHEMICAL NAME           : Pivalic acid, 2-benzylhydrazide
CAS REGISTRY NUMBER     : 306-19-4
BEILSTEIN REFERENCE NO. : 0744565
LAST UPDATED            : 199612
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C12-H18-N2-O
MOLECULAR WEIGHT        : 206.32
WISWESSER LINE NOTATION : 1X1&1&VMM1R
COMPOUND DESCRIPTOR     : Drug
                          Mutagen
SYNONYMS/TRADE NAMES :
   * N-Benzyl pivalhydrazide
   * Betamezid
   * Betamezide
   * Pivaloylbenzylhydrazine
   * Pivalylbenzhydrazine
   * Pivalyl benzylhydrazine
   * Pivazid
   * Pivhydrazine
   * Propanoic acid, 2,2-dimethyl-, 2-(phenylmethyl)hyrazide
   * Ro 4-1634
   * Tersavid
   * Tersavide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSCBAY Psychopharmacology Service Center, Bulletin.  (Bethesda, MD)  V.1-3,
   1961-65.  For publisher information, see PSYBB9.  Volume(issue)/page/year:
   2,17,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >290 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSCBAY Psychopharmacology Service Center, Bulletin.  (Bethesda, MD)  V.1-3,
   1961-65.  For publisher information, see PSYBB9.  Volume(issue)/page/year:
   2,17,1963
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >280 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSCBAY Psychopharmacology Service Center, Bulletin.  (Bethesda, MD)  V.1-3,
   1961-65.  For publisher information, see PSYBB9.  Volume(issue)/page/year:
   2,17,1963
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 5,343,1968
 
                            *** END OF RECORD ***