*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TP1386400
CHEMICAL NAME           : Platinate(2-),
                          (3-carboxy-2,3-dideoxypentarato(4-)-O(sup 4),O(sup
                          5))(1,2-cyclohexanediamine- N,N')-, dihydrogen,
                          (SP-4-3)-
CAS REGISTRY NUMBER     : 80611-44-5
LAST UPDATED            : 198511
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C12-H18-N2-O7-Pt
MOLECULAR WEIGHT        : 497.41
SYNONYMS/TRADE NAMES :
   * (Z)-(Cyclohexane-1,2-diammine)isocitratoplatinum(II)
   * cis-Isocitrato-(1,2-diamino-cyclohexan)-platin(II)
   * PHIC
   * Platinum(II), (cyclohexane-1,2-diammine)isocitrato-, (Z)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 143 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GEXXA8 German (East) Patent Document.  (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #158777
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 173 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GEXXA8 German (East) Patent Document.  (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #158777
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 236 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GEXXA8 German (East) Patent Document.  (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #158777
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 421 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GEXXA8 German (East) Patent Document.  (U.S. Patent and Trademark Office,
   Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year: #158777
 
                            *** END OF RECORD ***