*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TP1386400 CHEMICAL NAME : Platinate(2-), (3-carboxy-2,3-dideoxypentarato(4-)-O(sup 4),O(sup 5))(1,2-cyclohexanediamine- N,N')-, dihydrogen, (SP-4-3)- CAS REGISTRY NUMBER : 80611-44-5 LAST UPDATED : 198511 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C12-H18-N2-O7-Pt MOLECULAR WEIGHT : 497.41 SYNONYMS/TRADE NAMES : * (Z)-(Cyclohexane-1,2-diammine)isocitratoplatinum(II) * cis-Isocitrato-(1,2-diamino-cyclohexan)-platin(II) * PHIC * Platinum(II), (cyclohexane-1,2-diammine)isocitrato-, (Z)- *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 143 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GEXXA8 German (East) Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #158777 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 173 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GEXXA8 German (East) Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #158777 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 236 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GEXXA8 German (East) Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #158777 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 421 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GEXXA8 German (East) Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #158777 *** END OF RECORD ***