*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TP1500000
CHEMICAL NAME           : Platinate(2-), hexachloro-, dihydrogen, (OC-6-11)-
CAS REGISTRY NUMBER     : 16941-12-1
LAST UPDATED            : 199712
DATA ITEMS CITED        : 27
MOLECULAR FORMULA       : Cl6-Pt.2H
MOLECULAR WEIGHT        : 409.81
WISWESSER LINE NOTATION : H2 PT-G6
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Chloroplatinic acid
   * Chloroplatinic(IV) acid
   * Dihydrogen hexachloroplatinate
   * Dihydrogen hexachloroplatinate(2-)
   * Hexachloroplatinic acid
   * Hexachloroplatinic(IV) acid
   * Hexachloroplatinic(4+) acid, hydrogen-
   * Hydrogen hexachloroplatinate(4+)
   * NSC 4958
   * Platinic chloride
   * Platinum chloride (H2PtCl6)
   * Speier's catalyst
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 49 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Olfaction) - effect, not otherwise
   specified
   Behavioral - tremor
   Gastrointestinal - hypermotility, diarrhea
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB291-731
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 29097 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences.
   (Paris, France)  V.1-261, 1835-1965.  For publisher information, see CRASEV.
    Volume(issue)/page/year: 256,1043,1963
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 125 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EQSSDX Environmental Quality and Safety, Supplement.  (Stuttgart, Fed. Rep.
   Ger.)  V.1-5, 1975-76. Discontinued.  Volume(issue)/page/year: 1,1,1975
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Bacillus subtilis
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 77,109,1980

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 0.002 mg(Pt)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 0.002 mg(Pt)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   3,213,1971

   OSHA PEL (Gen Indu):8H TWA 0.002 mg(Pt)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 0.002 mg(Pt)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 0.002 mg(Pt)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 0.002 mg(Pt)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

                    *** OCCUPATIONAL EXPOSURE LIMITS ***
 
   OEL-ARAB Republic of Egypt:TWA 0.002 mg(Pt)/m3 (dust) JAN 1993
   
   OEL-AUSTRALIA:TWA 0.002 mg(Pt)/m3 JAN 1993
   
   OEL-BELGIUM:TWA 0.002 mg(Pt)/m3 JAN 1993
   
   OEL-DENMARK:TWA 0.002 mg(Pt)/m3 JAN 1993
   
   OEL-FINLAND:TWA 0.002 mg(Pt)/m3 JAN 1993
   
   OEL-GERMANY:TWA 0.002 mg(Pt)/m3 JAN 1993
   
   OEL-HUNGARY:STEL 0.002 mg(Pt)/m3 JAN 1993
   
   OEL-THE NETHERLANDS:TWA 0.002 mg(Pt)/m3 JAN 1993
   
   OEL-THE PHILIPPINES:TWA 0.002 mg(Pt)/m3 JAN 1993
   
   OEL-SWITZERLAND:TWA 0.002 mg(Pt)/m3 JAN 1993
   
   OEL-UNITED KINGDOM:TWA 0.002 mg(Pt)/m3 JAN 1993
   
   OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
   
   OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M4727
       No. of Facilities: 73 (estimated)
       No. of Industries: 2
       No. of Occupations: 3
       No. of Employees: 249 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M4727
       No. of Facilities: 62 (estimated)
       No. of Industries: 3
       No. of Occupations: 4
       No. of Employees: 1819 (estimated)
       No. of Female Employees: 1134 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Positive: B subtilis rec assay
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***