*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TP2200000 CHEMICAL NAME : Platinum (II), bis(cyclohexylammine)dichloro-, cis- CAS REGISTRY NUMBER : 38780-35-7 LAST UPDATED : 199509 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C12-H26-Cl2-N2-Pt MOLECULAR WEIGHT : 464.39 WISWESSER LINE NOTATION : L6TJ AZ 2 &G-PT-G -C COMPOUND DESCRIPTOR : Drug Mutagen SYNONYMS/TRADE NAMES : * cis-Dichlorobis(cyclohexylamine)platinum(II) * cis-Dicyclohexylamminedichloroplatinum (II) * cis-Had *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 36,420,1977 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 1 umol/plate REFERENCE : CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 26,179,1979 TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 30 ug/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 95,79,1982 TYPE OF TEST : DNA inhibition TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 40 mg/L REFERENCE : CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 35,189,1981 TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 40 mg/L REFERENCE : CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 35,189,1981 TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 40 mg/L REFERENCE : CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 35,189,1981 *** END OF RECORD ***