*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TP2205000 CHEMICAL NAME : Platinum (II), bis(cyclooctylammine)dichloro-, cis- CAS REGISTRY NUMBER : 62928-48-7 LAST UPDATED : 199012 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C16-H34-Cl2-N2-Pt MOLECULAR WEIGHT : 520.51 WISWESSER LINE NOTATION : L8TJ AZ 2 &G-PT-G -C COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * cis-Dicyclooctylamminedichloroplatinum (II) *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 660 mg/kg TOXIC EFFECTS : Kidney, Ureter, Bladder - other changes Tumorigenic - facilitates action of known carcinogen REFERENCE : CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 11,145,1975 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 135 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RRCRBU Recent Results in Cancer Research. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1965- Volume(issue)/page/year: 48,113,1974 *** END OF RECORD ***