*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TP2263100
CHEMICAL NAME           : Platinum (II), bis(pyrrolidine)dichloro-, trans-
CAS REGISTRY NUMBER     : 41575-86-4
LAST UPDATED            : 199012
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C8-H18-Cl2-N2-Pt
MOLECULAR WEIGHT        : 408.27
WISWESSER LINE NOTATION : T5MTJ 2 &G-PT-G -T
SYNONYMS/TRADE NAMES :
   * trans-Bis(pyrrolidine)dichloroplatinum (II)
   * trans-Dipyrrolidinedichloroplatinum (II)
   * Platinum (II), dipyrrolidinedichloro-, trans-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 72 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - other changes
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   11,145,1975
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 72 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RRCRBU Recent Results in Cancer Research.  (Springer-Verlag New York, Inc.,
   Service Center, 44 Hartz Way, Secaucus, NJ 07094)  V.1-    1965-
   Volume(issue)/page/year: 48,12,1974
 
                            *** END OF RECORD ***