*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TP2263100 CHEMICAL NAME : Platinum (II), bis(pyrrolidine)dichloro-, trans- CAS REGISTRY NUMBER : 41575-86-4 LAST UPDATED : 199012 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C8-H18-Cl2-N2-Pt MOLECULAR WEIGHT : 408.27 WISWESSER LINE NOTATION : T5MTJ 2 &G-PT-G -T SYNONYMS/TRADE NAMES : * trans-Bis(pyrrolidine)dichloroplatinum (II) * trans-Dipyrrolidinedichloroplatinum (II) * Platinum (II), dipyrrolidinedichloro-, trans- *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 72 mg/kg TOXIC EFFECTS : Kidney, Ureter, Bladder - other changes Tumorigenic - active as anti-cancer agent REFERENCE : CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 11,145,1975 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 72 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RRCRBU Recent Results in Cancer Research. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1965- Volume(issue)/page/year: 48,12,1974 *** END OF RECORD ***