*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TP2275810 CHEMICAL NAME : Platinum(II), (cyclobutane-1,1-dicarboxylato)((R)-2-methyl-1,4-buta nediammine)-, (Z)- CAS REGISTRY NUMBER : 110172-45-7 LAST UPDATED : 199412 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C11-H20-N2-O4-Pt MOLECULAR WEIGHT : 439.42 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * cis-1,1-Cyclobutanedicarboxylato-(2R)-2-methyl-1,4-butanediammineplatinu m(II) * (Z)-(Cyclobutane-1,1-dicarboxylato)((R)-2-methyl-1,4-butanediammine)plat inum(II) * NK 121 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 28 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 29,339,1988 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 14 mg/kg TOXIC EFFECTS : Gastrointestinal - nausea or vomiting REFERENCE : PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 29,339,1988 *** END OF RECORD ***