*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TP2275940 CHEMICAL NAME : Platinum(II), (cyclohexane-1,2-diammine)bis(methanesulfanato-O-)- CAS REGISTRY NUMBER : 65285-86-1 LAST UPDATED : 199107 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C8-H20-N2-O6-Pt-S2 MOLECULAR WEIGHT : 499.51 WISWESSER LINE NOTATION : L6TJ AZ BZ &WSO&1 2 &-PT- COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * (1,2-Cyclohexanediamine-N,N')bis(methanesulfanato-O-) platinum * NSC-263158 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 11 mg/kg TOXIC EFFECTS : Kidney, Ureter, Bladder - other changes REFERENCE : JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 67,201,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 15 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CTRRDO Cancer Treatment Reports. (Washington, DC) V.60-71, 1976-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 61,1519,1977 *** END OF RECORD ***