*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : TP2310000
CHEMICAL NAME : Platinum, diamminediaquo-, dinitrate
CAS REGISTRY NUMBER : 13601-02-0
LAST UPDATED : 199410
DATA ITEMS CITED : 4
MOLECULAR FORMULA : H10-N2-O2-Pt.N2-O6
MOLECULAR WEIGHT : 389.23
WISWESSER LINE NOTATION : .PT..ZH2.N-O3*2 QH2
COMPOUND DESCRIPTOR : Mutagen
Human
SYNONYMS/TRADE NAMES :
* Diaquodiammineplatinum dinitrate
* cis-Diaquodiammineplatinum(II) dinitrate
* Platinum (II), diaquodiammine-, dinitrate
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intradermal
SPECIES OBSERVED : Human
DOSE/DURATION : 40 mg/kg
TOXIC EFFECTS :
Skin and Appendages - primary irritation (after topical exposure)
Skin and Appendages - corrosive (after topical exposure)
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
35,2766,1975
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 5 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BICHBX Bioinorganic Chemistry. (New York, NY) V.1-9, 1971-78.
Volume(issue)/page/year: 2,187,1973
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 5 ug/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 48,139,1977
*** REVIEWS ***
TOXICOLOGY REVIEW
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc.,
2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961-
Volume(issue)/page/year: 65,315,1976
*** END OF RECORD ***