*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TP2482000
CHEMICAL NAME           : Platinum (II), diamminedinitrato-, trans-
CAS REGISTRY NUMBER     : 74006-35-2
LAST UPDATED            : 199201
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : H6-N4-O6-Pt
MOLECULAR WEIGHT        : 353.19
WISWESSER LINE NOTATION : .PT..ZH2.N-O3*2 -T
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * trans-Diamminedinitratoplatinum(II)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 11 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BICHBX Bioinorganic Chemistry.  (New York, NY)  V.1-9, 1971-78.
   Volume(issue)/page/year: 2,187,1973
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 33 umol/L
REFERENCE :
   NEOLA4 Neoplasma.  (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4-
      1957-  Volume(issue)/page/year: 34,379,1987

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 65,315,1976

 
                            *** END OF RECORD ***