*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TP2495100 CHEMICAL NAME : Platinum(II), dichlorodipyridine-, (Z)- CAS REGISTRY NUMBER : 15227-42-6 LAST UPDATED : 199410 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C10-H10-Cl2-N2-Pt MOLECULAR WEIGHT : 424.21 WISWESSER LINE NOTATION : T6NJ A-PT-GG- AT6NJ COMPOUND DESCRIPTOR : Mutagen SYNONYMS/TRADE NAMES : * cis-Dichloro(dipyridine)platinum(II) *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 131 mg/kg TOXIC EFFECTS : Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in bone marrow (not otherwise specified) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 65,315,1976 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 100 ug/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 95,79,1982 *** END OF RECORD ***