*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TP2497220 CHEMICAL NAME : Platinum (II), dichloro(4-methyl-o-phenylenediammine)- CAS REGISTRY NUMBER : 57948-13-7 LAST UPDATED : 199712 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C7-H10-Cl2-N2-Pt MOLECULAR WEIGHT : 388.18 WISWESSER LINE NOTATION : ZR BZ D1 &G-PT-G COMPOUND DESCRIPTOR : Drug Mutagen SYNONYMS/TRADE NAMES : * Dichloro(4-methyl-o-phenylenediammine)platinum(II) *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 23 mg/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : RCRVAB Russian Chemical Reviws (English Translation). Translation of USKHAB. (Royal Soc. of Chemistry, Distribution Centre, Blackhorse Rd., Letchworth, Herts SG6 1HN, UK) V.29- 1960- Volume(issue)/page/year: 50,353,1981 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 2500 nmol/L REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,459,1980 *** END OF RECORD ***