*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TP3922100 CHEMICAL NAME : Plumbane, acetoxytrimethyl- CAS REGISTRY NUMBER : 5711-19-3 LAST UPDATED : 199712 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C5-H12-O2-Pb MOLECULAR WEIGHT : 311.36 COMPOUND DESCRIPTOR : Organometallic SYNONYMS/TRADE NAMES : * Acetate de trimethylplomb * Acetoxytrimethylplumbane * Lead, acetoxytrimethyl- * Plumbane, (acetyloxy)trimethyl- * Trimethyllead acetate *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 66 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold REFERENCE : APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 24,17,1966 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 82 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold REFERENCE : APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 24,17,1966 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 34 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold REFERENCE : APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 24,17,1966 *** END OF RECORD ***