*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TQ8701000
CHEMICAL NAME           : Polyglycol laurate
CAS REGISTRY NUMBER     : 9004-81-3
OTHER CAS REGISTRY NOS. : 58392-04-4
LAST UPDATED            : 199710
DATA ITEMS CITED        : 9
MOLECULAR FORMULA       : (C2-H4-O)n-C12-H24-O2
SYNONYMS/TRADE NAMES :
   * G-2129
   * Glycols, polyethylene, monolaurate
   * Nopalcol 6-L
   * Polyoxyethylene-20 monolaurate
   * Poly(oxy-1,2-ethanediyl), alpha-(1-oxododecyl)-omega-hydroxy-
   * Polyoxyethylene monolaurate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 692 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   20PKA3 "Novye Dannye Po Toksikologii Redkikh Metalov Ikh Soedinenii," New
   Data on the Toxicology of Rare Metals and Their Compounds, Izrael'son, Z.I.,
   ed., Moscow, Izdatel'stvo "Meditsina," 1967  Volume(issue)/page/year:
   -,45,1967
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 38,428,1949
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 13687 gm/kg/2Y-C
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   2(1),59,1960
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 889 gm/kg/70D-C
TOXIC EFFECTS :
   Gastrointestinal - hypermotility, diarrhea
   Related to Chronic Data - death
REFERENCE :
   ABBIA4 Archives of Biochemistry and Biophysics.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.31-    1951-  Volume(issue)/page/year:
   34,249,1951

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 83953
       No. of Facilities: 1082 (estimated)
       No. of Industries: 28
       No. of Occupations: 49
       No. of Employees: 18551 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X6456
       No. of Facilities: 2120 (estimated)
       No. of Industries: 30
       No. of Occupations: 47
       No. of Employees: 59440 (estimated)
       No. of Female Employees: 27629 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-9314
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***