*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : TQ9694000
CHEMICAL NAME           : Poly(iminocarbonimidoylimino-1,6-hexanediyl),
                          monohydrochloride
CAS REGISTRY NUMBER     : 57029-18-2
LAST UPDATED            : 199501
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : (C7-H15-N3)n.Cl-H
SYNONYMS/TRADE NAMES :
   * Guanidine hydrochloride-hexamethylenediamine copolymer, sru
   * Poly(hexamethyleneguanidine) hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 630 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - acute pulmonary edema
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 57(3),11,1992
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 57(3),11,1992
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1537 mg/kg/61D-I
TOXIC EFFECTS :
   Liver - changes in liver weight
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - phosphatases
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - transaminases
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 57(3),11,1992
 
                            *** END OF RECORD ***