*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : TR0400000
CHEMICAL NAME : Polymethylmethacrylate
CAS REGISTRY NUMBER : 9011-14-7
OTHER CAS REGISTRY NOS. : 39404-54-1
53663-63-1
78206-73-2
86438-94-0
87210-32-0
LAST UPDATED : 199710
DATA ITEMS CITED : 18
MOLECULAR FORMULA : (C5-H8-O2)x
WISWESSER LINE NOTATION : /*1X*1&VO1/
COMPOUND DESCRIPTOR : Tumorigen
SYNONYMS/TRADE NAMES :
* Acronal S 320 D
* Acrylite
* Acryloid A-15
* Acrypet
* Acrypet M 001
* Acrypet V
* Acrypet VH
* Acrysol ase
* Akuripetto VH
* Altulor M 70
* A 21LV
* AO 10
* Cmw bone cement
* Crinothene
* Degalan LP 59/03
* Degalan S 85
* Delpet 50M
* Delpet 60N
* Delpet 80N
* Diakon
* Diakon LO 951
* Diakon MG
* Diakon MG 101
* Disapol M
* DV 400
* Elvacite
* Elvacite 2008
* Elvacite 2009
* Elvacite 2010
* Elvacite 2021
* Elvacite 2041
* Elvacite 6011
* Elvacite 6012
* Kallocryl K
* Kallodent 222
* Kallodent clear
* Kaneace PA 20
* K 120 N
* Korad
* LPT
* LPT 1
* LSO-M
* LSO-M 4B
* Lucite
* Lucite 30
* Lucite 47
* Lucite 120
* Lucite 129
* Lucite 130
* Lucite 140
* Lucite 147
* Lucite 180
* Metaplex NO
* Metaplex 4002T
* Methacrylic acid methyl ester polymers
* Methyl methacrylate homopolymer
* Methyl methacrylate polymer
* Methyl methacrylate resin
* 2-Methyl-2-propenoic acid methyl ester homopolymer
* MH 101-2
* 50N
* 50N (Polymer)
* Organic glass E 2
* Osteobond
* Osteobond surgical bone cement
* Palacos
* Paraglas
* Parapet 60N
* Paraplex P 543
* Paraplex P 681
* Perspex
* PLEX 8572-F
* Plexiglas
* Plexigum M 920
* PMMA
* PMMA-A
* Pontalite
* Repairsin
* Resarit 4000
* Rhoplex B 85
* Riston
* Romacryl
* Shinkolite
* SO 95
* SO 120
* SO 140
* Sol
* Sol 90
* Sol 95
* ST 1
* Stellon Pink
* ST 1 (Polymer)
* Sumipex B-LG
* Sumipex B-MH
* Sumipex-B MHD
* Sumipex LG
* Sumipex LO
* Sumipex MHO
* Superacryl AE
* Superacryl O
* Surgical simplex
* Surgical simplex P
* Tensol 7
* Torex G
* Vedril
* Vedril 5
* Vedril 8
*** HEALTH HAZARD DATA ***
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Implant
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 127 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
15,333,1955
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Implant
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 800 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Tumorigenic - tumors at site of application
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
(Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04-
Volume(issue)/page/year: 87,329,1954
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Implant
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 1882 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Tumorigenic - tumors at site of application
REFERENCE :
BJEPA5 British Journal of Experimental Pathology. (Blackwell Scientific
Pub. Ltd., POB 88, Oxford, UK) V.1- 1920- Volume(issue)/page/year:
45,21,1964
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Implant
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 13 gm/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year:
37,4367,1977
TYPE OF TEST : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE : Implant
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1280 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Tumorigenic - tumors at site of application
REFERENCE :
TUMOAB Tumori. (Casa Editrice Ambrosiana, Via G. Frua 6, 20146 Milan,
Italy) V.1- 1911- Volume(issue)/page/year: 52,165,1966
*** REVIEWS ***
IARC Cancer Review:Human No Adequate Data
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 19,187,1979
IARC Cancer Review:Animal Inadequate Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 19,187,1979
IARC Cancer Review:Group 3
IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49
Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year:
7,56,1987
TOXICOLOGY REVIEW
CMTVAS Cahiers de Medecine du Travail. (Association Professionnelle Belge
des Medecine du Travail, rue du Bultia, 6280 Gerpinnes, Belgium) V.1- 1963-
Volume(issue)/page/year: 10(3),49,1973
TOXICOLOGY REVIEW
ACEDAB Acta Endocrinologica, Supplementum (Copenhagen). (Periodica,
Skolegade 12 E, DK-2500 Valby, Denmark) No.1- 1948-
Volume(issue)/page/year: 185,296,1974
TOXICOLOGY REVIEW
SMJOAV Southern Medical Journal. (Southern Medical Assoc., POB 2446,
Birmingham, AL 35205) V.1- 1908- Volume(issue)/page/year: 67,1459,1974
TOXICOLOGY REVIEW
ETOXAC Essays in Toxicology. (Academic Press, Inc., 1 E. First St., Duluth,
MN 55802) V.1- 1969- Volume(issue)/page/year: 6,1,1975
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
NOHS - National Occupational Hazard Survey (1974)
NOHS Hazard Code - M0527
No. of Facilities: 2733 (estimated)
No. of Industries: 52
No. of Occupations: 51
No. of Employees: 27574 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - E0216
No. of Facilities: 7 (estimated)
No. of Industries: 1
No. of Occupations: 1
No. of Employees: 35 (estimated)
No. of Female Employees: 21 (estimated)
NOES - National Occupational Exposure Survey (1983)
NOES Hazard Code - M0527
No. of Facilities: 7530 (estimated)
No. of Industries: 92
No. of Occupations: 98
No. of Employees: 173808 (estimated)
No. of Female Employees: 74160 (estimated)
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
EPA TSCA Section 8(d) unpublished health/safety studies
EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
*** END OF RECORD ***