*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : TP8710000 CHEMICAL NAME : Podocarpa-8,11,13-trien-15-oic acid, 13-isopropyl- CAS REGISTRY NUMBER : 1740-19-8 BEILSTEIN REFERENCE NO. : 2059290 REFERENCE : 4-09-00-02389 (Beilstein Handbook Reference) LAST UPDATED : 199710 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C20-H28-O2 MOLECULAR WEIGHT : 300.48 SYNONYMS/TRADE NAMES : * Abietic acid, dehydro- * Dehydroabietic acid * (-)-Dehydroabietic acid * 13-Isopropylpodocarpa-8,11,13-trien-15-oic acid *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1710 mg/kg TOXIC EFFECTS : Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - ataxia REFERENCE : BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 18,42,1977 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 8400 mg/kg/28D-C TOXIC EFFECTS : Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) Biochemical - Metabolism (Intermediary) - Plasma proteins not involving coagulation REFERENCE : BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 18,42,1977 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2653 No. of Facilities: 1630 (estimated) No. of Industries: 16 No. of Occupations: 20 No. of Employees: 13811 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2653 No. of Facilities: 394 (estimated) No. of Industries: 8 No. of Occupations: 12 No. of Employees: 14625 (estimated) No. of Female Employees: 4688 (estimated) *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY EPA TSCA Section 8(d) unpublished health/safety studies EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998 *** END OF RECORD ***